Anadrol - Oxymetholone


Anadrol (Oxymetholone)
 
Summary:
·         Steroid Class: C-17 alpha alkylated oral steroid, DHT derived anabolic steroids
·         Anabolic/Androgenic Ratio: 320/45
·         Active Half-life: 8-9 Hours
·         Dosage: Men 25-150mg/day, Women 12.5-25mg/day
·         Usage: Mass gains, Strength, Bulking.
·         Estrogenic Side Effect: Yes (Strangely)
·         Androgenic Side Effect: Yes
 
Overview:
Anadrol is most probably is most second only to Dianabol when it comes to fame and widespread usage in the bodybuilding world. Additionally, Oxymetholone has considerable importance in the official medical field particularly for the treatment of anemia and considered a very effective treatment to help maintain lean body mass in HIV infected patients. Anadrol is usually considered by many as a harsh drug in terms of side effects, however, research findings prove otherwise differently.
Oxymetholone belongs to the family of Dihydrotestosterone (DHT) derived anabolic steroid, but with some modification in the chemical structure which allows Anadrol to remain active in muscle tissue, which is where and not rendered inactive by its reduction to other metabolites once it enters muscle tissue like its parent hormone.
When it comes to the general effectiveness of Anadrol for muscle-building purposes, As mentioned earlier studies and experience have demonstrated that it has notable anabolic effects on muscle-wasting AIDS patients, which in fact allowed those patients to gain 8kg of weight. Due to this ability, Anadrol is currently prescribed almost primarily for AIDS patients and muscle wasting diseases.
 
Dosage and Effect:
The typical mens does of Anadrol is 50-150 mg/day, and in some advanced cases larger doses such as 200 mg/day are used, but that is quite rare because of Anadrol liver toxicity and also when properly stacked with one or more other anabolic steroids, there is no real further benefit from going over 100 mg/day.
Womens dose is usually within the range of 12.5-25 mg/day, preferably taken as divided doses. The lower range of 12.5 mg/day is remarkably effective and more than enough.
Oxymetholone inclusion is a cycle is aimed towards bulking and muscle weight gain and strength-gaining. Anadrol is a very poor choice when cutting and contest preparation is the main goal. Having said that, Oxymetholone can indeed be used as an aid for accelerating fat loss but to a very moderate degree due to its estrogenic effects, primarily water-retention and bloating.
Anadrol usage is commonly reserved for kickstarting a cycle with one or more injectable compounds for the first 4 – 6, or as a finisher in order to boost the end of a cycle to allow the user to finish off with an impressive strength and size gains an allow a swift switch into the PCT (Post Cycle Therapy) phase due to the short half-life of Anadrol.
 
Anadrol Stacking:
Anadrol is a class 2 AAS which means it has a poor binding affinity to the androgen receptor and it expresses most of its effect through other means and mechanisms. Therefore, stacking Anadrol to 50 mg/day of Dianabol which also a class 2 steroid gives little added benefit let alone the added toxicity to the liver. In contrast, an Anadrol – Trenbolone stack can produce dramatic results. 
Anavar stacks very well with Oxymetholone and can results in a great improvement, even though hepatoxicity can be an issue.
 
Side Effect:
Anadrol is usually perceived to have a harsh side effect profile in bodybuilding, which is not really the case according to experience. Those side effects are usually and principally estrogenic, due to elevated levels of estrogen and can be managed by the use of an AI (Aromatase Inhibitor).
Oxymetholone does not itself aromatize and does not have estrogenic activity, the explanation to its estrogenic side effect is it interferes with estrogen metabolism. Whatever the cause may be, keeping E2 under control is essential while using Anadrol, similar to any other aromatizing steroid.
The main side effect of Anadrol is its hepatoxicity or liver problems as it is an alkylated oral anabolic steroid. This issue can be addressed but limiting the duration of usage to 4  - 6 weeks maximum and allowing a long enough time off after ever period of use.
Also, a liver supporting supplementation is highly recommended to support any Anadrol cycle.
·      Estrogenic side effects: As mentioned before, Oxymetholone does not convert into estrogen. However, it is one of the mysterious characteristics of Anadrol.
 It expresses a high level of estrogenic activity causing water retention, bloating, gynecomastia, and elevated blood pressure. those can be managed with the use of Aromatase Inhibitors such as Exemestane (Aromasin) and Arimidex.
·      Androgenic side effects:  Anadrol does not convert into DHT but rather is metabolized into 17-alpha-methyl dihydrotestosterone (Mestanolone). Mestanolone is a stronger androgen, and therefore androgenic side effects are present. Those include oily skin, acne, male pattern baldness, benign or temporary prostatic hyperplasia.
 
Post Cycle Therapy:
PCT can start immediately after the last Anadrol dose if no other long-acting steroid was used due to its short half-life of 6-8 hours and therefore clears the body fast allowing the process of recovery to start.